We investigate neural mechanisms of isolated focal dystonia and tremor to determine the disorder-specific pathophysiology and develop novel diagnostic tools and therapeutic strategies for these patients. We use a variety of experimental approaches, including multimodal neuroimaging, advanced machine-learning, clinical-behavioral testing, neuropathology, and genetics. Explore our website to learn more about our research, discoveries and team.
The Dystonia and Speech Motor Control Laboratory is supported by supported by the National Institutes of Health - National Institute on Deafness and Other Communication Disorders (NIDCD) and National Institute of Neurological Disorders and Stroke (NINDS), Department of Defense, Amazon Web Services, Jazz Pharmaceuticals, Mass General Brigham Innovation.
Tweets by @SimonyanLab
- Involvement of these structures points to indirect action of #botulinum #toxin treatment on the #dystonic sensorimotor network, likely via modulation of motor sequence planning and coordination. Read the open access article now: t.co/kxSO2GrzPD
- Short-term effect following the injection cycle: left precuneus is modulated in #dystonia patients who are treated & benefiting from injections Long-term effect over 1-28 treatment years: prefrontal- cerebellar axis is most prominently modulated in those w/ 6-12 treatment years
- Very pleased to see our latest paper on #botulinum #toxin effects on pathophysiological brain activity in #dystonia out in @GreenJournal! t.co/AFHiSgz1W6
- @DorisWangLab Congratulations, Doris!!